Pence has written a letter saying he doesn’t agree with using the 25th so that option is closed leaving impeachment. The article of impeachment calls out insurrection and rebellion creating a plan B should the senate not vote for removal that allows Trump to be prosecuted for Insurrection and rebellion under the 14th.
Either impeachment or the 14th will prevent Trump from holding office. The 14th is easier than impeachment as it only takes a majority not a super majority (2/3rds) and wouldn’t take up Senate time for a trial. It does however involve the courts after Congress votes for it.
Four Republicans (Katko, Cheney, Kinzinger, Upton) currently support impeachment, and McConnell is considering support as he does not see it as partisan and wants to see the evidence.
It is hard to understand why Pence won’t invoke the 25th which the House passed today (1-12-21) when he had to be evacuated with his wife, daughter and brother because mobs wanted to hang him and Trump didn’t care enough about his well being to even check on his safety.